Бион-6 Bion 6 (Kosmos 1514 Космос 1514) – 1983

byun sik's or cosmos 1514 was biomedical space a flight research mission that was launched on December 12th 1983 it was part of the BI and satellite program when rhesus monkeys were flown into orbit implanted with sensors to permit monitoring of Croton artery blood flow additionally 18 pregnant white rats were sent to be used for studies of the effects of microgravity and radiation the rats subsequently produced normal litters the mission concluded after five days this was the first time the Soviet space agency flew monkeys in space coming 22 years after the Soviet Union started putting humans into space the mission differed markedly from earlier cosmos flights both in terms of Soviet scientific goals and in the degree of cooperation required between the United States and the USSR the two countries had to interact at a high level to integrate u.s. experiment hardware with the Soviet spacecraft and instrumentation systems experiments focused on the effect of weightlessness on various physiological parameters a study of circadian rhythms was concerned with the synchronization of primate motor activity body temperature and skin temperature rhythms to fixed light / dark cycle and to each other blood pressure and flow were monitored to evaluate short and long-term changes in these parameters changes in calcium metabolism were studied to help determine the effect of weightlessness on the skeleton the term rhesus monkeys macaca mulatta flown on board were about three years of age and each weighed approximately four kilograms by was a constraint in selecting animals for flight this was because the Soviet vestibule experiment required that the flight restraint ouches oscillate vertically within the animal capsules the monkeys were conditioned to sit in the restraint pouches and perform tasks for food rewards tasks included pressing a lever with their feet and tracking a moving light with their eyes monkeys were also trained to eat and drink from food and juice dispensers the monkeys in both the flight and control groups were implanted with blood pressure flow cuffs and other sensors to measure several physiological parameters an experiment was conducted to investigate spaceflight effect it's on the sensory development of the rats that spent part of their prenatal gestation period in space 10 pregnant female Wistar rats Rattus norvegicus were flown ground control groups contained the same number of rats at the start of the flight or control experiments the rats registration day 13 of their 21-day cycle

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