In Vitro Fertilisation (IVF) explained simply



IVF explained simply since the first IVF baby Lewis Brown was born in England in 1978 more than five million children have been born using this technique we're going to explain in plain language each step of the IVF process once medical histories have been studied ovarian stimulation is the first step it starts from the onset of menstruation and less about nine days is purpose is to obtain an adequate number of good quality o sites or eggs in order to adapt the medication to the body's response which varies even within each cycle we continue the ovarian follicle development through ultrasound scans and the occasional blood tests to achieve this we follow the medication timetable outlined and prescribed by the gynecologist which is designed for each patient when the time comes we will use an injection of HCG overdraw to provoke the final maturity of all the eggs that have been developed and monitored this will be synchronized 36 hours beforehand the eggs are collected in about 10 minutes in an outpatient basis the procedure is completed under light sedation and with the help of vaginal ultrasound and with minimal discomfort and risk to the patient a gynecologist aspirates follicular fluid which is then immediately studied by the biologists who then prepare the retrieved eggs for fertilization at the same time a biologist prepares and capacities the semen to increase its fertilizing abilities whenever possible we prefer to be as natural as possible and let's apply classic IVF that is we leave thousands of spermatozoids around the egg so that the strongest among them fertilizes it if semen quality is reduced we apply the EXCI technique which gives nature a helping hand it involves putting a single pre-selected sperm inside the egg we also know that just as it happens in nature only 60 to 70 percent of eggs retrieved are normal and mature only 60 set to 70 percent of these are fertilized not all fertilized embryos develop normally throughout the process which can last up to 5 days we evaluate the characteristics of embryonic development and transfer one or two of the embryos which have the best chance of achieving pregnancy what are the advantages firstly it represents natural selection of the best embryos as the weaker ones will not survive the days following fertilization and so the survivors are the most likely to succeed secondly it allows for the possibility of being able to freeze suitable embryos for future transfers using a technique called vitrification this avoids all the previous process of stimulation collection and embryo culture for a new attempt in the event of the first cycle failing or rather if you would like other children in the future after 18 hours we find out the number of eggs showing the first signs of fertilization 48 hours later on day 3 the embryos now have between 7 and 9 cells and depending on their quality number and quantity the time of transfer is decided from the fourth day the embryos are called blastocyst the cells are already compacted and can even be seen moving the 5th day is the maximum amount of time the embryos can be outside the womb now the most anticipated and desired event takes place the transfer there is no need for sedation it is a painless process where the gynecologist transfers the resulting embryo into the womb using a thin ultrasound guided catheter which allows him or her to see the uterus and the best site to deposit the embryo after about 10 or 11 days a maternal blood test is performed to confirm the success of the procedure this looks at the presence of be HCG in the blood this is the hormone that early embryos produced it's value helps us evaluate the pregnancy as well as the possibility of having twins pregnancies and future children conceived through assisted reproduction techniques develop in the same way as those achieved naturally

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